CRISPR
CRISPR is a gene-editing technology, derived from a bacterial immune system, that cuts and alters specific DNA sequences.
CRISPR takes its name from repeated DNA sequences found in bacteria and archaea and the associated defense system, and the term is also used for the gene-editing technology built on it. In CRISPR-Cas9 editing, a guide RNA directs the Cas9 enzyme to a target sequence, where it cuts the DNA. In 2012 Jennifer Doudna and Emmanuelle Charpentier showed the system could be used as a gene-editing tool, work that earned them the 2020 Nobel Prize in Chemistry.
AI models are used to predict how effectively guide RNAs act on their targets and whether they may act at unintended sites.
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